肝星状细胞的激活与凋亡相关信号通路研究进展(5)
[33]Miyahara T,Schrum L,Rippe R,et al.Peroxisome proliferator-activated receptors and hepatic stellate cell activation.J Biol Chem.2000,275(46):35715-35722.
[34]Hazra S,Xiong S,Wang J,et al.Peroxisome prolifer-ator-activated receptor gamma induces a phenotypic switch from activated to quiescent hepatic stellate cells.J Biol Chem,2004,279(12):11392-11401.
[35]Friedman SL.The answer:angiotensin Ⅱ.The question :what do inflammation,oxidant stress and fibrogenesis have in common.J Hepatol.2004,40(6):1050-1052.
[36]Griendling KK,Ushio-Fukai M.Reactive oxygen species as mediators of angiotensin Ⅱ signaling.Regul Pept.2000,91(1-3):21-27.
[37]Li X,Meng Y,Cai SX,et al.Angiotensin Ⅱ and aldosterone stimulate alPhal-(I)Procollagen mRNA expression in hepatic stellate cells via activation of ERK1/2 and AP-1.Zhonghua Yi Xue Za Zhi.2005,85:1831-1835.
[38]Hellemans K,Verbuyst P,Quartier E,et al.Differential modulation of rat hepatic stellate phenotype by natural and synthetic retinoids.Hepatology.2004,39(1):97-108.
[39]Milliano MT,Luxon BA.Rat hepatic stellate cells become retinoid unresponsive during activation.Heptol Res.2005,33(3):225-233.
[40]Fiorucci S,Antonelli E,Rizzo G, et al.The nuclear receptor SHP mediates inhibition of hepatic stellate cells by FXR and protects against liver fibrosis.Gastroenterology.2004,127(5):149-1512.
[41]Huang GC,Zhang JS,Tang QQ.Involvement of C/EBP-alpha gene in in-vitro activation of rat hepatic stellate cells.Biochem BiophysRes Commun,2004,324(4):1309-1318.
[42]Saile B,Matthes N,Neubauer K,et al.Rat liver myofibroblasts and hepatic stellate cells differ in CD95-mediated apoptosis and response to TNF-alpha.Am J Physiol Gastrointest Liver Physiol,2002,283(2):435-444.
【收稿日期】2011-04-19
(本文编辑：郎威), 百拇医药(尤俊勇 王效民)
[34]Hazra S,Xiong S,Wang J,et al.Peroxisome prolifer-ator-activated receptor gamma induces a phenotypic switch from activated to quiescent hepatic stellate cells.J Biol Chem,2004,279(12):11392-11401.
[35]Friedman SL.The answer:angiotensin Ⅱ.The question :what do inflammation,oxidant stress and fibrogenesis have in common.J Hepatol.2004,40(6):1050-1052.
[36]Griendling KK,Ushio-Fukai M.Reactive oxygen species as mediators of angiotensin Ⅱ signaling.Regul Pept.2000,91(1-3):21-27.
[37]Li X,Meng Y,Cai SX,et al.Angiotensin Ⅱ and aldosterone stimulate alPhal-(I)Procollagen mRNA expression in hepatic stellate cells via activation of ERK1/2 and AP-1.Zhonghua Yi Xue Za Zhi.2005,85:1831-1835.
[38]Hellemans K,Verbuyst P,Quartier E,et al.Differential modulation of rat hepatic stellate phenotype by natural and synthetic retinoids.Hepatology.2004,39(1):97-108.
[39]Milliano MT,Luxon BA.Rat hepatic stellate cells become retinoid unresponsive during activation.Heptol Res.2005,33(3):225-233.
[40]Fiorucci S,Antonelli E,Rizzo G, et al.The nuclear receptor SHP mediates inhibition of hepatic stellate cells by FXR and protects against liver fibrosis.Gastroenterology.2004,127(5):149-1512.
[41]Huang GC,Zhang JS,Tang QQ.Involvement of C/EBP-alpha gene in in-vitro activation of rat hepatic stellate cells.Biochem BiophysRes Commun,2004,324(4):1309-1318.
[42]Saile B,Matthes N,Neubauer K,et al.Rat liver myofibroblasts and hepatic stellate cells differ in CD95-mediated apoptosis and response to TNF-alpha.Am J Physiol Gastrointest Liver Physiol,2002,283(2):435-444.
【收稿日期】2011-04-19
(本文编辑：郎威), 百拇医药(尤俊勇 王效民)