糖尿病与肿瘤关系研究现状(2)
综上所述,糖尿病诱发恶性肿瘤的机制和糖尿病患者不同脏器对肿瘤的易感性是非常复杂且微妙的,是否还存在他方面的机制尚需进行更加深入的临床研究。且以上这些研究多在欧洲和北美人群中进行,对于亚洲人群,尤其是中国人群中,尚未见大样本的研究分析,糖尿病及其进程与肿瘤发生的相关性有待进一步证实。
参考文献
[1]Herdan G.The frequency of cancer in diabetes mellitus.Br J Cancer,1960,14(4):49-56.
[2]Grosse H.Diabetes and cancer.Arch Geschwulstforsch,1969,33(1):49-56.
[3]季尚玮,郭宏华.糖尿病与消化系统肿瘤关系的研究进展.国际消化病杂志,2006,26(1):61-63.
, 百拇医药
[4]杨前勇,邹大进.糖尿病中的氧化损伤与抗氧化研究进展.国际内分泌代谢杂志,2006,26(增刊):8-10.
[5]Brownlee M.The pathobiology of diabetic complication：a unifying mechanism.Diabetes,2005,3(54):1615-1625.
[6]何杨,吉兆宁,王潞,等.乳腺癌中IGF-I表达及其与细胞增殖和凋亡相关基因关系.临床与实验病理学杂志,2007,23(3)：363-365.
[7]卢圣爱,陈自平,刘倩,等.胃癌患者血清胰岛素样生长因子-II检测及其临床意义.中国现代普通外科进展，2007,10(3)：216-218.
[8]Levi F,Pasche C,Lucchini F，et,al.Diabetesmellitus,family history,and colorectal cancer.J EpidemiolCommu Health,2002,56(6):479-480.
, 百拇医药
[9]Yang YX,Hennessy S,Lewis JD.Type 2 diabetesmellitus and the risk of colorectal cancer.Clin Gastroenterol Hepatol,2005,3(6):587-594.
[10]Sandhu MS，Luben R，Khaw KT. Self reported non-insulin de-pendentdiabetes,family history,and risk of prevalent colorectal cancer population based,cross sectional study.EpidemiolCommu Health,2001,55(11):804-805.
[11]王荣欣,胡水清.糖尿病与结直肠癌发病关系探究.实用医学杂志，2007,23(22)：3518-3520.
, 百拇医药
[12]Hu FB, Manson JE,Liu S,et al.Prospective study ofadulton-setdiabetes mellitus( type 2) and risk of colorectal cancer in women.J Natl Cancer Inst,1999,91(6):542-547.
[13]Nilsen TI,Vatten LJ.Prospective study of colorectal cancer risk and physical activity,diabetes,blood glucose and BMI:explo-ring the hyperinsulinaemia hypothesis. Br J Cancer,2001,84(3):417-422.
[14]Chari ST,Leibson CL,Rabe KG，et al.Probability of pancreatic cancer following diabetes:a population-based study.Gastroenterology，2005，3(129):504-511.
, http://www.100md.com
[15]DeMeo MT.Pancreatic cancer and sugar diabetes.Nutr Rev,2001,59(4):112-115.
[16]Jee SH,Ohrr H,Sull JW,et al.Fasting serum glucose level and cancer risk in Korean men and women.JA-MA,2005,12(293):194-202.
[17]张学宏,高玉堂,邵常霞，等.既往疾病史与胰腺癌关系的流行病学研究.肿瘤,2006,1(26):37-39.
[18]张伟,于晓峰,孙皎,等.老年胰腺癌与糖尿病关系分析.老年医学与保健,2008,14(1):42-45.
[19]王育瑶,赵立,顾呜宇,等.胰腺癌与糖尿病关联的探讨.中国癌症杂志,2006,16(11):973-975.
, 百拇医药
[20]Davila JA,Morgan RO,Shaib Y,et al.Diabetes increa-ses the risk of hepatocellular carcinoma in the United States:a population based case control study.Gut,2005,54:533-539.
[21]Wu AH, Yu MC,Tseng CC, et al.Diabetes and risk of breast cancer in Asian-American women.Carcinogene-sis,2007,28(7):1561-1566.
[22]佐藤哲子.脂肪细胞因子与肿瘤.日本医学介绍,2007,28(12):564-566.
[23]梁文霞,郎云星.2型糖尿病合并恶性肿瘤22例分析.实用糖尿病杂志,2008,4(5):23-24.
, 百拇医药
[24]Inoue M,Iwasaki M,Otani T,et al.Diabetes mellitus and the risk of caner:results from a large-scale population-based cohort study in Japan.Arch Intern Med,2006,7(166):1871-1877.
[25]骆梅青，李锡清.肺癌与2型糖尿病的相关性研究.中国肿瘤临床与康复，2010,17(3):199-202.
[26]王克安,李天麟,向红丁.中国糖尿病流行特点研究——糖尿病和糖耐量低减患病率调查.中华流行病学杂志,2007,19(5):282-285.
【收稿日期】2011-06-07
(本文编辑：刘曾敏), 百拇医药(韦华 王民登)
参考文献
[1]Herdan G.The frequency of cancer in diabetes mellitus.Br J Cancer,1960,14(4):49-56.
[2]Grosse H.Diabetes and cancer.Arch Geschwulstforsch,1969,33(1):49-56.
[3]季尚玮,郭宏华.糖尿病与消化系统肿瘤关系的研究进展.国际消化病杂志,2006,26(1):61-63.
, 百拇医药
[4]杨前勇,邹大进.糖尿病中的氧化损伤与抗氧化研究进展.国际内分泌代谢杂志,2006,26(增刊):8-10.
[5]Brownlee M.The pathobiology of diabetic complication：a unifying mechanism.Diabetes,2005,3(54):1615-1625.
[6]何杨,吉兆宁,王潞,等.乳腺癌中IGF-I表达及其与细胞增殖和凋亡相关基因关系.临床与实验病理学杂志,2007,23(3)：363-365.
[7]卢圣爱,陈自平,刘倩,等.胃癌患者血清胰岛素样生长因子-II检测及其临床意义.中国现代普通外科进展，2007,10(3)：216-218.
[8]Levi F,Pasche C,Lucchini F，et,al.Diabetesmellitus,family history,and colorectal cancer.J EpidemiolCommu Health,2002,56(6):479-480.
, 百拇医药
[9]Yang YX,Hennessy S,Lewis JD.Type 2 diabetesmellitus and the risk of colorectal cancer.Clin Gastroenterol Hepatol,2005,3(6):587-594.
[10]Sandhu MS，Luben R，Khaw KT. Self reported non-insulin de-pendentdiabetes,family history,and risk of prevalent colorectal cancer population based,cross sectional study.EpidemiolCommu Health,2001,55(11):804-805.
[11]王荣欣,胡水清.糖尿病与结直肠癌发病关系探究.实用医学杂志，2007,23(22)：3518-3520.
, 百拇医药
[12]Hu FB, Manson JE,Liu S,et al.Prospective study ofadulton-setdiabetes mellitus( type 2) and risk of colorectal cancer in women.J Natl Cancer Inst,1999,91(6):542-547.
[13]Nilsen TI,Vatten LJ.Prospective study of colorectal cancer risk and physical activity,diabetes,blood glucose and BMI:explo-ring the hyperinsulinaemia hypothesis. Br J Cancer,2001,84(3):417-422.
[14]Chari ST,Leibson CL,Rabe KG，et al.Probability of pancreatic cancer following diabetes:a population-based study.Gastroenterology，2005，3(129):504-511.
, http://www.100md.com
[15]DeMeo MT.Pancreatic cancer and sugar diabetes.Nutr Rev,2001,59(4):112-115.
[16]Jee SH,Ohrr H,Sull JW,et al.Fasting serum glucose level and cancer risk in Korean men and women.JA-MA,2005,12(293):194-202.
[17]张学宏,高玉堂,邵常霞，等.既往疾病史与胰腺癌关系的流行病学研究.肿瘤,2006,1(26):37-39.
[18]张伟,于晓峰,孙皎,等.老年胰腺癌与糖尿病关系分析.老年医学与保健,2008,14(1):42-45.
[19]王育瑶,赵立,顾呜宇,等.胰腺癌与糖尿病关联的探讨.中国癌症杂志,2006,16(11):973-975.
, 百拇医药
[20]Davila JA,Morgan RO,Shaib Y,et al.Diabetes increa-ses the risk of hepatocellular carcinoma in the United States:a population based case control study.Gut,2005,54:533-539.
[21]Wu AH, Yu MC,Tseng CC, et al.Diabetes and risk of breast cancer in Asian-American women.Carcinogene-sis,2007,28(7):1561-1566.
[22]佐藤哲子.脂肪细胞因子与肿瘤.日本医学介绍,2007,28(12):564-566.
[23]梁文霞,郎云星.2型糖尿病合并恶性肿瘤22例分析.实用糖尿病杂志,2008,4(5):23-24.
, 百拇医药
[24]Inoue M,Iwasaki M,Otani T,et al.Diabetes mellitus and the risk of caner:results from a large-scale population-based cohort study in Japan.Arch Intern Med,2006,7(166):1871-1877.
[25]骆梅青，李锡清.肺癌与2型糖尿病的相关性研究.中国肿瘤临床与康复，2010,17(3):199-202.
[26]王克安,李天麟,向红丁.中国糖尿病流行特点研究——糖尿病和糖耐量低减患病率调查.中华流行病学杂志,2007,19(5):282-285.
【收稿日期】2011-06-07
(本文编辑：刘曾敏), 百拇医药(韦华 王民登)