色素上皮衍生因子与胰岛素抵抗的相关性(4)
[20] Arimura T，Miura S， Sugihara M，et al.Association between plasma levels of pigment epithelium-derived factor and renal dysfunction in patients with coronary artery disease[J].Cardiol J，2011，18(5)：515-520.
[21] Gao C L，Zhu C，Zhao Y P，et al.Mitochondrial dysfunction is induced by high levels of glucose and free fatty acids in 3T3-L1 adipocytes[J].Molecular and Cellular Endocrinology，2010，320(1)：25-33.
[22] Gaetano C，Colussi C，Capogrossi M C.PEDF，PPAR-δ，p53：Deadly circuits arise when worlds collide[J].Cardiovascular Research，2007，76(2)：195-196.
[23] Kim F，Pham M，Luttrell I，et al.Toll-like receptor-4 mediates vascular inflammation and insulin resistance in diet-induced obesity[J].Circulation Research，2007，100(11)：1589-1596.
[24] Chen L，Zhang S S M，Barnstable C J，et al.PEDF induces apoptosis in human endothelial cells by activating p38 MAP kinase dependent cleavage of multiple caspases[J].Biochemical and Biophysical Research Communications，2006，348(4)：1288-1295.
[25] Gratton J P，Morales-Ruiz M，Kureishi Y，et al.Akt down-regulation of p38 signaling provides a novel mechanism of vascular endothelial growth factor-mediated cytoprotection in endothelial cells[J].Journal of Biological Chemistry，2001，276(32)：30359-30365.
(收稿日期：2016-10-21), http://www.100md.com(李翔 杨铭 董茜)
[21] Gao C L，Zhu C，Zhao Y P，et al.Mitochondrial dysfunction is induced by high levels of glucose and free fatty acids in 3T3-L1 adipocytes[J].Molecular and Cellular Endocrinology，2010，320(1)：25-33.
[22] Gaetano C，Colussi C，Capogrossi M C.PEDF，PPAR-δ，p53：Deadly circuits arise when worlds collide[J].Cardiovascular Research，2007，76(2)：195-196.
[23] Kim F，Pham M，Luttrell I，et al.Toll-like receptor-4 mediates vascular inflammation and insulin resistance in diet-induced obesity[J].Circulation Research，2007，100(11)：1589-1596.
[24] Chen L，Zhang S S M，Barnstable C J，et al.PEDF induces apoptosis in human endothelial cells by activating p38 MAP kinase dependent cleavage of multiple caspases[J].Biochemical and Biophysical Research Communications，2006，348(4)：1288-1295.
[25] Gratton J P，Morales-Ruiz M，Kureishi Y，et al.Akt down-regulation of p38 signaling provides a novel mechanism of vascular endothelial growth factor-mediated cytoprotection in endothelial cells[J].Journal of Biological Chemistry，2001，276(32)：30359-30365.
(收稿日期：2016-10-21), http://www.100md.com(李翔 杨铭 董茜)