With the fact that the hypothalamus control behaviors such as eating， the FTO genes and hypothalamus must have associations. The feeding center is in the lateral hypothalamus. Moreover， it can stimulate hunger， which plays a huge role in food intake and obesity [13]. FTO is actually expressed with a large amount in the hypothalamic sites controlling feeding behavior， and it can influence food intake [14]. Indeed， scientists found that FTO protein is abundantly expressed in mouse brain ......