抑癌基因与肺癌的早期诊断(3)
6 Sozzi G,et al .Association between cigarette smoking and FHIT gene alterations in lung cancer . Cancer Res:1997,57(11):2121-2123
7 Wistuball,et al .Molecular damage in the bronchial epithelium of current and former smokers. J Natl Cancer Inst . 1997;89:1366-1373
8 Minna JD, et al . Molecular pathogenesis of lung cancer . Lung Cancer 2000,29(Suppl 2):37-38.
9 Mao L, et al. Molecular change in early carcinogenesis of the lung. Lung Cancer 2000;29(Suppl 2):40.
, 百拇医药
10 Sozzi G,et al. Loss of FHIT function in lung cancer and preinvasive bronchial leisions. Cancer Res 1998;58(22)5032-5037.
11 Thiberville L,et al . Evidence of cumulative gene losses with progression of premalignant epithelial lessions to carcinoma of the bronchus . Cancer Res 1995;55:5133-5 l 39
12 Kishimoto Y et al. Allele- Specitic loss in chromosome 9p loic in preneoplastic lesions accompanying NSCLC. J Natl cancer Inst 1995;87(16): 1224-1229
, 百拇医药
13 Devos S et al. Alteration of CDKN2 in non-small cell lung cancer. Genes Chromosome Cancer 1995;14: 164-170
14 Belinsky SA, et al. Aberrant methylation of pl6 is an early event in lung cancer and potential biomarker for early diagnosis. Proc Natl Acad Sci USA, 1998;95(20):11891-11896
15 Ahrendt Sa. et al. Molecular detection of tumor cells in bronchoalvelar lavage fluid from patients with early stage lung cancer. J Natl Cancer Inst,1991 ;(4):332-339
, http://www.100md.com
16 Aikou O,et al. Mutation in the pl6INK4,p15INK4 in primary and metastatic lung cancer. Cancer Res 1995 ;54:1448-1451
17 Kinoshita 1 et al. Altered p16INK4 and retinoblastoma protein status in NSCLC:potential synergistic effect with altered p53 protein on proliferative activity. Cancer Res 1996;56:5557-5562
18 Harris C C et al N Eng J Med ,1993;329:1318-1327
19 Mao L,et al Detections of oncogene mutation in sputum precede diagnosis of lung cancer .Cancer Res, 1994;54(&): 1634-1637
, http://www.100md.com
20 Westra WH et al Am J Surg Pathol, 1993, 17:213-220
21 PulsieuxA et al Cancer Res 1991;51 :6185-6190
22 PonticielloA et al P53 immunohistochemistry can identity bronchial dysplatic lesions proceedings to lung cancer ,a prospective study. Eur Respir J. 2000; l 5(3):547-552
23 Bennett WP et al P53 protein accumulates frequently in early bronchial neoplasia. Cancer Res 1993;53:4817-4822
24 Bramilla E et al. P53 mutation immunochenotype and deregulation of p53 ,transcriptions
pathway in precursor bronchial lesions of lung cancer. Clinic cancer Res,1998;4(7): 1609-1618, http://www.100md.com(廖日强)
7 Wistuball,et al .Molecular damage in the bronchial epithelium of current and former smokers. J Natl Cancer Inst . 1997;89:1366-1373
8 Minna JD, et al . Molecular pathogenesis of lung cancer . Lung Cancer 2000,29(Suppl 2):37-38.
9 Mao L, et al. Molecular change in early carcinogenesis of the lung. Lung Cancer 2000;29(Suppl 2):40.
, 百拇医药
10 Sozzi G,et al. Loss of FHIT function in lung cancer and preinvasive bronchial leisions. Cancer Res 1998;58(22)5032-5037.
11 Thiberville L,et al . Evidence of cumulative gene losses with progression of premalignant epithelial lessions to carcinoma of the bronchus . Cancer Res 1995;55:5133-5 l 39
12 Kishimoto Y et al. Allele- Specitic loss in chromosome 9p loic in preneoplastic lesions accompanying NSCLC. J Natl cancer Inst 1995;87(16): 1224-1229
, 百拇医药
13 Devos S et al. Alteration of CDKN2 in non-small cell lung cancer. Genes Chromosome Cancer 1995;14: 164-170
14 Belinsky SA, et al. Aberrant methylation of pl6 is an early event in lung cancer and potential biomarker for early diagnosis. Proc Natl Acad Sci USA, 1998;95(20):11891-11896
15 Ahrendt Sa. et al. Molecular detection of tumor cells in bronchoalvelar lavage fluid from patients with early stage lung cancer. J Natl Cancer Inst,1991 ;(4):332-339
, http://www.100md.com
16 Aikou O,et al. Mutation in the pl6INK4,p15INK4 in primary and metastatic lung cancer. Cancer Res 1995 ;54:1448-1451
17 Kinoshita 1 et al. Altered p16INK4 and retinoblastoma protein status in NSCLC:potential synergistic effect with altered p53 protein on proliferative activity. Cancer Res 1996;56:5557-5562
18 Harris C C et al N Eng J Med ,1993;329:1318-1327
19 Mao L,et al Detections of oncogene mutation in sputum precede diagnosis of lung cancer .Cancer Res, 1994;54(&): 1634-1637
, http://www.100md.com
20 Westra WH et al Am J Surg Pathol, 1993, 17:213-220
21 PulsieuxA et al Cancer Res 1991;51 :6185-6190
22 PonticielloA et al P53 immunohistochemistry can identity bronchial dysplatic lesions proceedings to lung cancer ,a prospective study. Eur Respir J. 2000; l 5(3):547-552
23 Bennett WP et al P53 protein accumulates frequently in early bronchial neoplasia. Cancer Res 1993;53:4817-4822
24 Bramilla E et al. P53 mutation immunochenotype and deregulation of p53 ,transcriptions
pathway in precursor bronchial lesions of lung cancer. Clinic cancer Res,1998;4(7): 1609-1618, http://www.100md.com(廖日强)