右美托咪定对无创通气AECOPD患者镇静的安全性及有效性研究(4)
[15]Constantin JM，Momon A，Mantz J，et al. Efficacy and safety of sedation with dexmedetomidine in critical care patients：A meta-analysis of randomized controlled trial[J].Anaesth Crit Care Pain Med，2015，35(1)：7-15
[16]Ebert TJ，Hall JE，Barney JA，et al. The effects of increasing plasma concentrations of dexmedetomidine in humans[J].Anesthesiology，2000，93(2)：382-394.
[17]Prielipp RC，Wall MH，Tobin JR，et al.Dexmedetomi-dineinduced sedation in volunteers decreases regional and global cerebral blood flow[J]. Anesth Analg，2012，95(4)：1052-1059.
[18]Shehabi Y，Ruettimann U，Adamson H，et al. Dexmedetomidine infusion for more than 24 hours in critically ill patients： Sedative and cardiovascular effects[J]. Intensive Care Med，2004，30(12)：2188-2196.
[19]Yu T，Li Q，Liu L，et al.Different effects of propofol and dexmedetomidine on preload dependency in endotoxemic shock with norepinephrine infusion[J].J Surg Res，2015， 198(1)：185-191.
[20]Kim KN，Lee HJ，Kim SY，et al.Combined use of dexmedetomidine and propofol in monitored anesthesia care：A randomized controlled study[J].BMC Anesthesiol，2017，17(1)：34.
[21]Jo YY，Kim HS，Lee KC，et al. Consort the effect of intraoperative dexmedetomidine on hemodynamic responses during emergence from nasotracheal intubation after oral surgery[J]. Medicine(Baltimore)，2017，96(16)：e6661.
(收稿日期：2017-10-11), 百拇医药(俞国峰 应利君)
[16]Ebert TJ，Hall JE，Barney JA，et al. The effects of increasing plasma concentrations of dexmedetomidine in humans[J].Anesthesiology，2000，93(2)：382-394.
[17]Prielipp RC，Wall MH，Tobin JR，et al.Dexmedetomi-dineinduced sedation in volunteers decreases regional and global cerebral blood flow[J]. Anesth Analg，2012，95(4)：1052-1059.
[18]Shehabi Y，Ruettimann U，Adamson H，et al. Dexmedetomidine infusion for more than 24 hours in critically ill patients： Sedative and cardiovascular effects[J]. Intensive Care Med，2004，30(12)：2188-2196.
[19]Yu T，Li Q，Liu L，et al.Different effects of propofol and dexmedetomidine on preload dependency in endotoxemic shock with norepinephrine infusion[J].J Surg Res，2015， 198(1)：185-191.
[20]Kim KN，Lee HJ，Kim SY，et al.Combined use of dexmedetomidine and propofol in monitored anesthesia care：A randomized controlled study[J].BMC Anesthesiol，2017，17(1)：34.
[21]Jo YY，Kim HS，Lee KC，et al. Consort the effect of intraoperative dexmedetomidine on hemodynamic responses during emergence from nasotracheal intubation after oral surgery[J]. Medicine(Baltimore)，2017，96(16)：e6661.
(收稿日期：2017-10-11), 百拇医药(俞国峰 应利君)