客家人群同型半胱氨酸与冠心病的相关性研究(3)
综上所述,由于CHD的高发病率及死亡率,临床医师有必要对患者进行全方位、多层次的治疗,而Hcy对于CHD的发现具有重要的预测价值,对于CHD的预防、控制以及治疗存在积极影响,可以指导临床医生采取有效的干预措施帮助患者进行治疗。
参考文献
[1]张琛涛,莫新玲.冠心病、高血压与血清同型半胱氨酸、超敏C反应蛋白的相关性[J].中国老年学杂志,2013,33(5):1035-1037.
[2]邓远琼,张志娟,李宏翔,等.血管内皮功能及同型半胱氨酸对冠心病的预测价值研究[J].中国全科医学,2013,16(37):3672-3675.
[3]周坤元,李水彬,成钢卫,等.客家人群颈动脉闭塞的临床特点及相关危险因素分析[J].中国实用神经疾病杂志,2017,20(10):26-29.
, 百拇医药
[4] Mehlig K,Leander K,de Faire U,et al.The association between plasma homocysteine and coronary heart disease is modified by the MTHFR 677C>T polymorphism[J].Heart,2013,99(23):1761-1765.
[5]叶任高,陆再英.内科学[M].6版.北京:人民卫生出版社,2006:323.
[6] D’Aquila P,Rose G,Bellizzi D,et al.Epigenetics and aging[J].Maturitas,2013,74(2):130-136.
[7] Doering LV,Moser DK,Riegel B,et al.Persistent comorbid symptoms of depression and anxiety predict mortality in heart disease[J].Int J Cardiol,2010,145(2):188-192.
, 百拇医药
[8] Bronze-da-Rocha E.MicroRNAs expression profiles in cardiovascular diseases[J].Biomed ResInt,2014,2014:985408.
[9] Polovina M M,Potpara T S.Endothelial dysfunction in metabolic and vascular disorders[J].Postgrad Med,2014,126(2):38-53.
[10] Shu L,Park JL,Byun J,et al.Decreased nitric oxide bioavailability in a mouse model of Fabry disease[J].J Am Soc Nephrol,2009,20(9):1975-1985.
[11]張立建,李慧敏,潘锦汉,等.冠心病患者同型半胱氨酸水平特点及叶酸对其的干预效果[J].中国生化药物杂志,2017,37(5):61-62,65.
, 百拇医药
[12] Hoffman M.Hypothesis:hyperhomocysteinemia is an indicator of oxidant stress[J].Med Hypotheses,2011,77(6):1088-1093.
[13]叶志荣,林勇军,洪娜娇,等.血清同型半胱氨酸及铁蛋白水平与冠心病患者冠状动脉狭窄程度的相关性[J].中国老年学杂志,2016,36(24):6103-6105.
[14]章祎,王湛,蔡梦娇.血清同型半胱氨酸和超敏C反应蛋白与冠心病、高血压疾病发展的相关性[J].广东医学,2016,37(13):1989-1990.
[15] Han L,Wu Q,Wang C,et al.Homocysteine,Ischemic Stroke,and Coronary Heart Disease in Hypertensive Patients A Population-Based,Prospective Cohort Study[J].Stroke,2015,46(7):1777-1786.
, http://www.100md.com
[16]王琦,周艳辉,王康鸣.同型半胱氨酸、胱抑素C、C反应蛋白与冠心病的相关性研究[J].重庆医学,2016,45(18):2556-2558.
[17]宋艳东,陶英,王苏,等.冠心病患者同型半胱氨酸、血尿酸水平与冠脉病变的相关性[J].中华急诊医学杂志,2017,26(4):430-433.
[18] Vosbergen S,Janzen J,Stappers P J,et al.A qualitative participatory study to identify experiences of coronary heart disease patients to support the development of online self-management services[J].Int J Med Inform,2013,82(12):1183-1194.
[19]鄢高亮,王栋,乔勇,等.高同型半胱氨酸水平对冠心病严重程度及支架置入治疗预后的影响[J].中华心血管病杂志,2015,43(11):943-947.
[20]刘英,白晟遥,高辉,等.降同型半胱氨酸疗法对冠心病介入治疗后患者的疗效[J].心血管康复医学杂志,2015,24(6):640-643.
(收稿日期:2018-01-10) (本文编辑:董悦), 百拇医药(陈志龙 钟凯 何宇东)
参考文献
[1]张琛涛,莫新玲.冠心病、高血压与血清同型半胱氨酸、超敏C反应蛋白的相关性[J].中国老年学杂志,2013,33(5):1035-1037.
[2]邓远琼,张志娟,李宏翔,等.血管内皮功能及同型半胱氨酸对冠心病的预测价值研究[J].中国全科医学,2013,16(37):3672-3675.
[3]周坤元,李水彬,成钢卫,等.客家人群颈动脉闭塞的临床特点及相关危险因素分析[J].中国实用神经疾病杂志,2017,20(10):26-29.
, 百拇医药
[4] Mehlig K,Leander K,de Faire U,et al.The association between plasma homocysteine and coronary heart disease is modified by the MTHFR 677C>T polymorphism[J].Heart,2013,99(23):1761-1765.
[5]叶任高,陆再英.内科学[M].6版.北京:人民卫生出版社,2006:323.
[6] D’Aquila P,Rose G,Bellizzi D,et al.Epigenetics and aging[J].Maturitas,2013,74(2):130-136.
[7] Doering LV,Moser DK,Riegel B,et al.Persistent comorbid symptoms of depression and anxiety predict mortality in heart disease[J].Int J Cardiol,2010,145(2):188-192.
, 百拇医药
[8] Bronze-da-Rocha E.MicroRNAs expression profiles in cardiovascular diseases[J].Biomed ResInt,2014,2014:985408.
[9] Polovina M M,Potpara T S.Endothelial dysfunction in metabolic and vascular disorders[J].Postgrad Med,2014,126(2):38-53.
[10] Shu L,Park JL,Byun J,et al.Decreased nitric oxide bioavailability in a mouse model of Fabry disease[J].J Am Soc Nephrol,2009,20(9):1975-1985.
[11]張立建,李慧敏,潘锦汉,等.冠心病患者同型半胱氨酸水平特点及叶酸对其的干预效果[J].中国生化药物杂志,2017,37(5):61-62,65.
, 百拇医药
[12] Hoffman M.Hypothesis:hyperhomocysteinemia is an indicator of oxidant stress[J].Med Hypotheses,2011,77(6):1088-1093.
[13]叶志荣,林勇军,洪娜娇,等.血清同型半胱氨酸及铁蛋白水平与冠心病患者冠状动脉狭窄程度的相关性[J].中国老年学杂志,2016,36(24):6103-6105.
[14]章祎,王湛,蔡梦娇.血清同型半胱氨酸和超敏C反应蛋白与冠心病、高血压疾病发展的相关性[J].广东医学,2016,37(13):1989-1990.
[15] Han L,Wu Q,Wang C,et al.Homocysteine,Ischemic Stroke,and Coronary Heart Disease in Hypertensive Patients A Population-Based,Prospective Cohort Study[J].Stroke,2015,46(7):1777-1786.
, http://www.100md.com
[16]王琦,周艳辉,王康鸣.同型半胱氨酸、胱抑素C、C反应蛋白与冠心病的相关性研究[J].重庆医学,2016,45(18):2556-2558.
[17]宋艳东,陶英,王苏,等.冠心病患者同型半胱氨酸、血尿酸水平与冠脉病变的相关性[J].中华急诊医学杂志,2017,26(4):430-433.
[18] Vosbergen S,Janzen J,Stappers P J,et al.A qualitative participatory study to identify experiences of coronary heart disease patients to support the development of online self-management services[J].Int J Med Inform,2013,82(12):1183-1194.
[19]鄢高亮,王栋,乔勇,等.高同型半胱氨酸水平对冠心病严重程度及支架置入治疗预后的影响[J].中华心血管病杂志,2015,43(11):943-947.
[20]刘英,白晟遥,高辉,等.降同型半胱氨酸疗法对冠心病介入治疗后患者的疗效[J].心血管康复医学杂志,2015,24(6):640-643.
(收稿日期:2018-01-10) (本文编辑:董悦), 百拇医药(陈志龙 钟凯 何宇东)