摘要：目的通过比较附子毒性古今认识，为现代附子毒性研究提供重要研究方向和思路。方法对古代和现代文献中附子毒性的基本认识、毒效关系与禁忌症、用药剂量、控毒方法、解毒方法等方面进行比较，梳理出古今附子毒性认识的异同。结果古今在附子的基本认识、毒效关系与禁忌症、配伍控毒等方面无明显差异，且现代研究可补充和完善古代认识。而在用药剂量、其他控毒方法、中毒解救等方面有一定差异。结论现代研究应在用药剂量、炮制方法、煎煮法等方面加强研究力度。

    关键词：附子；毒性；古今认识

    doi: 10.3969/j.issn.2095-5707.2014.03.019

    Comparison of Recognition on the Toxicity of Fuzi in the Ancient and Modern Times

    Ao Hui, Cao Xiaoyu*

    (Chengdu University of Traditional Chinese Medicine, Chengdu Sichuan 611137, China)

    Abstract: Objective To provide an important research direction and some ideas for modern researches on toxicity of Fuzi by comparing the toxicity recognition recorded in the ancient and modern literature. Methods This article compared the toxicity recorded in the ancient and modern literature from the aspects of the basic recognition, the relationship of toxicity-effect, the contraindications, the dosage, the toxicity controlling methods, detoxifying methods, etc, and sorted out the differences and similarities of the recognition on the toxicity of Fuzi in the ancient and modern times. Results This article explained that in the ancient and modern times, the basic recognition, the relationship of toxicity-effect, the contraindications, and the compatibility of Fuzi showed no remarkable differences, and the modern researches could supplement and perfect the ancient understanding. However, there were also some differences in the dosage, the other toxicity controlling methods, detoxifying methods and so on. Conclusion The modern researches should focus on the dosage, the processing methods and the decoction of Fuzi. ......