News release from the 2002 plenary session of global human genome congress held in Shanghai from April 14-17: the research on systemic lupus erythematosus (SLE) started already from the gene level by Chinese and American scientists; the Chinese and Japanese scientists advocated the joint establishment of "Gene SNP data base of the Asian race".
An epidemiological survey in 32.7 thousand populace conducted by the researchers of the laboratory of clinical immunology and rheumatoid disease in Shanghai Institute of Immunology, Renji Hospital of Shanghai Second Medical University revealed that the incidence of SLE in Chinese is 700/100 thousand, and in the females it is as high as 1130/100 thousand, a figure 8-10 folds higher than that of the European and American population. An American scientist well known in the world for her research on gene of breast cancer and with her scholastic achievement in SLE study considered that the scientists had already found out the pathogenesis of SLE being the mutations of a few genes and that the Sino-American scientists will join hands to find out mechanism of the interactions of these genes, to fundamentally overcome this persistent disease. Renji Hospital has already joined the Sino-American collaborative research for pursuing the pathogenesis of autoimmune disease at the gene level.
Another discovery was that 70% of human gene posses the character of being shared, and the additional 30% results in the discrepancy in different races at various regions of the world. For this purpose, the Chinese and Japanese scientists advocated joint establishment of "Gene SNP database of the Asian race" to study the polymorphism of mono-ribonucleotide, for an investigation of the susceptibility to disease condition in individual populace and their difference in drug reactions, thereby accelerating the discovery of gene agents in accommodation to the gene characteristics of the Asian people.
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